Showing posts with label hypertensive heart disease. Show all posts
Showing posts with label hypertensive heart disease. Show all posts

Wednesday, October 3, 2018

What are the treatments for hypertensive heart disease?

What are the treatments for hypertensive heart disease?
What are the treatments for hypertensive heart disease?

Treatment

1. Control blood pressure early
Early blood pressure compliance is the primary task in the treatment of hypertensive heart disease, and the SBP target value should be considered <140mmHg.

2. The importance of reversing LVH
The Framinghan Heart Study has confirmed a reduction in LVH and a decrease in cardiovascular mortality through long-term follow-up. Reversal of LVH includes non-drug therapy: optimized lifestyle, low-salt diet; weight control; alcohol restriction; reduction of certain sympathetic active hormones, such as elevated catecholamines, renin angiotensin system (RAS) activation stress status. Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-converting enzyme receptor antagonist (ARB) may prevent LVH and myocardial fibrosis in antihypertensive drugs. Animal experiments and human studies have also confirmed that calcium antagonists (CCB) can reverse LVH.

What are the diagnostic methods for hypertensive heart disease?

What are the diagnostic methods for hypertensive heart disease?
What are the diagnostic methods for hypertensive heart disease?
Diagnosis

1.History
Have a history of hypertension.

2. Clinical manifestations
In the heart function compensation period, only the general symptoms of hypertension; when the heart function is not fully compensated, the symptoms of left heart failure may occur, the light person only has difficulty breathing after exertion, and the severe person has squat breathing, cardiogenic asthma. Even acute pulmonary edema occurs; patients with chronic disease can develop right heart failure and eventually lead to heart failure.

What tests do you need to do for hypertensive heart disease?

What tests do you need to do for hypertensive heart disease?
What tests do you need to do for hypertensive heart disease?
An examination

1.Electrocardiogram
The electrocardiogram can be normal, and left ventricular hypertrophy and strain can also occur. RV5+SV1>4.0mV (male), RV5+SV1> 3.5mV (female), the ST segment of the R-wave dominant lead can be moved down, or the T wave is inverted, and the electric axis is left-biased.

2. Chest X-ray film
In addition to dilatation of the aorta, the aorta extends tortuosity. The upper edge of the aortic arch can reach or exceed the level of the sterno-lock joint. The aortic node protrudes to the left and the heart is depressed. It becomes a typical "aortic heart".

3. Echocardiography
(1) M-mode echocardiography

  • Compartment interval and left ventricular posterior wall thickness increase ventricular septum and left ventricular posterior wall showed uniform symmetry thickening, when the interventricular septum and left ventricular posterior wall absolute thickness greater than 12mm, can diagnose left ventricular hypertrophy.
  • The increase of left ventricular myocardial weight is an important index for evaluating cardiac hypertrophy. In the past, the actual value of myocardial weight can only be understood through autopsy. In recent years, a large number of clinical studies have shown that the weight of myocardium obtained by echocardiography is used. Values ​​are highly correlated with autopsy results. Therefore, the American Society of Echocardiography recommends the use of the Devereux correction formula to calculate myocardial weight and myocardial weight index.

Left ventricular mass = 0.8 × 1.04 [(LVDd + IVST + PWT) - LVDd) + 0.6
Left ventricular mass index (g/m) = left ventricular weight / body surface area
Left ventricular mass index normal value male 135g / m, female 125g / m

(2) Two-dimensional echocardiography left ventricular long axis, short axis section showed left ventricular wall hypertrophy, left ventricular hypertrophy with centripetal hypertrophy, a few irregular irregular hypertrophy, centripetal hypertrophy ventricular septum and left ventricular posterior wall Symmetrical hypertrophy, irregular type is asymmetrical hypertrophy between the ventricular septum and the posterior wall of the left ventricle, the left ventricular cavity is normal or slightly reduced, the amplitude of the wall motion is enhanced, and the left atrium can be slightly increased. Two-dimensional ultrasound is applied. Cardiac measurements of left ventricular myocardium were more accurate than M-mode echocardiography, and heart failure during systolic dysfunction, as well as enlargement of the left atrium and left ventricle.

(3) Doppler echocardiography showed high systolic systole in early stage, increased peak velocity of aortic blood flow, normal cardiac output, normal ejection fraction, and frequent abnormal changes in mitral blood flow spectrum. When left ventricular hypertrophy and diastolic compliance decline, left ventricular filling resistance increases. In order to maintain cardiac output, the main compensatory mechanism is to increase atrial filling pressure, which is characterized by prolonged left ventricular isovolumic diastolic phase and decreased E peak peak velocity. Acceleration time, deceleration time, prolonged early diastolic duration, increased peak peak velocity of A peak, and decreased E/A ratio, reflecting impairment of left ventricular diastolic function.

(4) Tissue Doppler mitral annulus velocity The main manifestation is decreased diastolic function. It is characterized by mitral annulus early diastolic velocity (E') and late diastolic velocity (A'), E'/A'<1. For patients with impaired myocardial relaxation, E' decreases in the basal state and does not increase as the pre-load increases as in normal subjects. Thus, E' reduction is one of the earliest manifestations of diastolic dysfunction. The European Society of Cardiology guidelines believe that E/E'≥15 can diagnose left ventricular diastolic dysfunction. When E/E' is 8-15, another diagnostic evidence of non-invasive left ventricular diastolic dysfunction, such as mitral or pulmonary venous flow spectrum, left ventricular mass index, etc., is required.

What are the clinical manifestations of hypertensive heart disease?

What are the clinical manifestations of hypertensive heart disease?
What are the clinical manifestations of hypertensive heart disease?
Clinical manifestation

1. Early
Early performance is generally atypical, patients may have no obvious symptoms or only mild discomfort such as headache, chest tightness, etc. These symptoms are mainly the general symptoms of hypertension, no particularity.

2. Progress period
In high blood pressure, the arterial blood pressure is too high, which hinders the heart from pumping out blood. The heart's long-term high-load work shows an increase in cardiac hypertrophy and stiffness, which eventually leads to obstruction of the pulmonary vein blood entering the heart, forming pulmonary congestion. When the heart muscle is hypertrophied, the oxygen demand is increased, and the blood supply is relatively insufficient, which often leads to heart attack. The clinical manifestations of diastolic heart failure and systolic heart failure are similar, and it is difficult to identify clinically. The clinical features of heart failure caused by hypertension are as follows:

What is hypertensive heart disease? What are the pathophysiological changes in hypertensive heart disease?

Poor long-term control of hypertension can cause changes in cardiac structure and function, including hypertensive heart disease, including: early left ventricular diastolic dysfunction, left ventricular hypertrophy (LVH), progressive development of myocardial systolic dysfunction, and ultimately heart failure, Studies have shown that 70% of heart failure is caused by high blood pressure; there may be associated coronary heart disease, atrial fibrillation and other cardiac complications.
What is hypertensive heart disease? What are the pathophysiological changes in hypertensive heart disease?
Pathophysiological changes

1. Left ventricular hypertrophy (LVH)
LVH is a compensatory change of myocardial pressure on blood pressure, and the myocardial contractility is enhanced to maintain sufficient cardiac output, but long time can cause myocardial cell hypertrophy, muscle fiber thickening, degeneration, decreased capillary relative density, etc. change. Early myocardial remodeling phenomenon, that is, centripetal remodeling, myocardial cell hypertrophy, but the number does not increase, the arrangement changes, collagen fibers increase, and gradually collagen accumulation exceeds 20% to fibrosis, in order to replace the loss of function of cells, resulting in The heart is hypertrophic, and finally the increase in volume load causes centrifugal hypertrophy. Hypertension LVH is first reflected in the ventricular septal thickening, which is a common part of the heart size circulation, and plays an important role in the left and right ventricular systolic function.