What is hypertensive heart disease? What are the pathophysiological changes in hypertensive heart disease?

Poor long-term control of hypertension can cause changes in cardiac structure and function, including hypertensive heart disease, including: early left ventricular diastolic dysfunction, left ventricular hypertrophy (LVH), progressive development of myocardial systolic dysfunction, and ultimately heart failure, Studies have shown that 70% of heart failure is caused by high blood pressure; there may be associated coronary heart disease, atrial fibrillation and other cardiac complications.

What is hypertensive heart disease? What are the pathophysiological changes in hypertensive heart disease?

Pathophysiological changes

1. Left ventricular hypertrophy (LVH)
LVH is a compensatory change of myocardial pressure on blood pressure, and the myocardial contractility is enhanced to maintain sufficient cardiac output, but long time can cause myocardial cell hypertrophy, muscle fiber thickening, degeneration, decreased capillary relative density, etc. change. Early myocardial remodeling phenomenon, that is, centripetal remodeling, myocardial cell hypertrophy, but the number does not increase, the arrangement changes, collagen fibers increase, and gradually collagen accumulation exceeds 20% to fibrosis, in order to replace the loss of function of cells, resulting in The heart is hypertrophic, and finally the increase in volume load causes centrifugal hypertrophy. Hypertension LVH is first reflected in the ventricular septal thickening, which is a common part of the heart size circulation, and plays an important role in the left and right ventricular systolic function.